Methyl Guanine Methyl Transferase Methylation Status and Epidermal Growth Factor Receptor expression in a cohort of Egyptian glioblastoma patients
| Autor: | Soheir M. Hamam, Doaa A Abdelmonsif, Iman M. Talaat, Rasha A. Nassra, Bassma M. El Sabaa |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Chemotherapy Methyl guanine methyl transferase Temozolomide biology business.industry medicine.medical_treatment Genomic data Methylation medicine.disease Molecular biology 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis Cohort Cancer research biology.protein Medicine Epidermal growth factor receptor business Glioblastoma medicine.drug |
| Zdroj: | Egyptian Journal of Pathology. 36:282-288 |
| ISSN: | 1687-4277 |
| DOI: | 10.1097/01.xej.0000511094.91402.70 |
| Popis: | IntroductionGlioblastoma multiforme is the most frequently occurring primary brain tumour with a dismal prognosis. Chemotherapy with an alkylating agent such as Temozolomide (TMZ) confers a significant survival benefit. Genomic data elucidating pathogenetic mechanisms underlying gliomagenesis includ |
| Databáze: | OpenAIRE |
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