Diagnostic endoscopic submucosal dissection for colorectal lesions with suspected deep invasion
| Autor: | Clara Yzet, Adrien Patenotte, Timothée Wallenhorst, Fabien Subtil, Sarah Leblanc, Marion Schaefer, Thomas Walter, Thomas Lambin, Tanguy Fenouil, Pierre Lafeuille, Jean-Baptiste Chevaux, Romain Legros, Florian Rostain, Jérôme Rivory, Jérémie Jacques, Vincent Lépilliez, Mathieu Pioche |
|---|---|
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Endoscopy. 55:192-197 |
| ISSN: | 1438-8812 0013-726X |
| Popis: | Background Endoscopic submucosal dissection (ESD) is potentially a curative treatment for T1 colorectal cancer under certain conditions. The aim of this study was to evaluate the feasibility and effectiveness of ESD for lesions with a suspicion of focal deep invasion. Methods In this retrospective multicenter study, consecutive patients with colorectal neoplasia displaying a focal ( Results 124 patients benefited from 126 diagnostic dissection attempts for FDIP lesions. Dissection was feasible in 120/126 attempts (95.2 %) and, where possible, the en bloc and R0 resection rates were 95.8 % (115/120) and 76.7 % (92/120), respectively. Thirty-three resections (26.2 %) were for very low risk tumors, so considered curative, and 38 (30.2 %) were for low risk lesions. Noncurative R0 resections were for lesions with lymphatic or vascular invasion (LVI; n = 8), or significant budding (n = 9), and LVI + budding combination (n = 4). Conclusion ESD is feasible and safe for colorectal lesions with an FDIP ≤ 15 mm. It was curative in 26.6 % of patients and could be a valid option for a further 30.6 % of patients with low risk T1 cancers, especially for frail patients with co-morbidities. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|