Induction of cytochrome P-450 and mixed function oxygenase activity by low concentrations of polychlorinated biphenyls in marine fish Zosterisessor ophiocephalus(Pall.)

Autor:	Margherita Turchetto, G. Campesan, Laura Tallandini, Valentino U. Fossato, C. Nasci
Rok vydání:	1991
Předmět:	Pollutant chemistry.chemical_classification Cytochrome biology Chemistry Health Toxicology and Mutagenesis Cytochrome P450 Mussel Aquatic Science chemistry.chemical_compound Enzyme Biochemistry Toxicity biology.protein Pyrene Food science Enzyme inducer
Zdroj:	Aquatic Toxicology. 19:281-290
ISSN:	0166-445X
DOI:	10.1016/0166-445x(91)90053-c
Popis:	The results of five experiments with the marine fish Zosterisessor ophiocephalus (Pall.) exposed to relatively low concentrations of PCBs (Aroclor 1254) in water and fed with uncontaminated and contaminated mussel tissues are reported. The data obtained indicate that PCBs accumulated in fish liver are responsible for induction of hepatic benzo[a]pyrene hydroxylase (BPH) activity as well as for the higher cytochrome P-450 content in PCB treated fish. It also appears that, when MFO activity is related to PCB liver content, the relationship seems to be relatively independent of exposure and/or administration modalities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3f0ed68d3b644391f34bfb583e4e9af6 https://doi.org/10.1016/0166-445x(91)90053-c Zobrazit plný text záznamu