Anacine, a New Benzodiazepine Metabolite of Penicillium aurantiogriseum Produced with Other Alkaloids in Submerged Fermentation
| Autor: | Peter G. Mantle, John N. Bilton, Karen A. Gurney, Jane M. Boyes-Korkis, Richard N. Sheppard, Julia Penn |
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| Rok vydání: | 1993 |
| Předmět: |
Pharmacology
Stereochemistry Metabolite Alkaloid Organic Chemistry Pharmaceutical Science Industrial fermentation Fungi imperfecti Biology biology.organism_classification Analytical Chemistry Spore chemistry.chemical_compound Complementary and alternative medicine Biochemistry chemistry Biosynthesis Drug Discovery Penicillium Molecular Medicine Penicillium aurantiogriseum |
| Zdroj: | Journal of Natural Products. 56:1707-1717 |
| ISSN: | 1520-6025 0163-3864 |
| Popis: | A novel bensodiasepine metabolite of an isolate of Penicillium aurantiogriseumfrom Yugoslavia has been characterised from spectral and biosynthetic evidence. The compound, anacine [1], has been produced on the 60-lirer fermenter scale after extensive sporulation induced by batched Ca ++ , and its biosynthesis was preceded by that of the diketopiperasine fructigenine A [7] for which additional spectral and biosynthetic data have been obtained |
| Databáze: | OpenAIRE |
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