Hypervalent-iodine(iii ) oxidation of hydrazones to diazo compounds and one-pot nickel(ii )-catalyzed cyclopropanation
| Autor: | Haixuan Liu, Yunyang Wei, Chun Cai |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Iodosobenzene
010405 organic chemistry Cyclopropanation Hypervalent molecule chemistry.chemical_element General Chemistry 010402 general chemistry Iodine 01 natural sciences Catalysis 0104 chemical sciences Cyclopropane chemistry.chemical_compound Nickel chemistry Materials Chemistry Organic chemistry Diazo |
| Zdroj: | New Journal of Chemistry. 40:674-678 |
| ISSN: | 1369-9261 1144-0546 |
| DOI: | 10.1039/c5nj02378e |
| Popis: | A one-pot process for the catalytic cyclopropanation of various alkenes with unsubstituted hydrazones is described. Iodosobenzene (PhIO) was found to be a competent oxidant of hydrazones to diazo compounds. Ni(OH)2 was chosen as an effective and cheap metal catalyst. The cyclopropane products can be generated efficiently (5 min–4 h) in moderate to good yields (42–91%) under mild (80 °C) and neat conditions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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