Two Concurrent Cancers in a 19-Year-Old Patient: Yolk Sac Ovarian Tumor and Metastatic Gastrointestinal Tract Malignancy—Case Report
| Autor: | Paweł Knapp, Wiktor Bortnik, Paweł Guzik, Piotr Sitnik, Marta Baczewska, Jakub Dobroch, Piotr Bernaczyk |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
030219 obstetrics & reproductive medicine business.industry Obstetrics and Gynecology Cancer General Medicine Gynecologic oncology medicine.disease Debulking Malignancy Krukenberg tumor 03 medical and health sciences Ovarian tumor 0302 clinical medicine Pediatrics Perinatology and Child Health medicine 030212 general & internal medicine Radiology Differential diagnosis business Ovarian cancer |
| Zdroj: | Journal of Pediatric and Adolescent Gynecology. 34:561-565 |
| ISSN: | 1083-3188 |
| DOI: | 10.1016/j.jpag.2021.02.104 |
| Popis: | Background Two concurrent malignancies present in a young person is an extremely rare condition. Diagnoses of gastric cancer primarily concern older patients. There are very few reports of concomitant Krukenberg tumor and germ-cell ovarian malignancy. Case A 19-year-old girl was admitted to the gynecologic oncology department with symptoms of advanced malignancy. Radiological imaging revealed disseminated neoplastic disease with bulky adnexal tumors. Cytoreductive surgery was performed, achieving no visible disease (T = 0 cm). The final pathology report confirmed metastatic mixed adenoneuroendocrine carcinoma (MANEC) in both ovaries, originating from the gastrointestinal tract. Moreover, the primary germ cell yolk sac tumor was found in the left ovary. Conclusion In cases of concomitant gastric and ovarian tumors, metastatic disease (Krukenberg tumor) should be considered in the differential diagnosis. This concerns even adolescent patients. In particular cases, including tumors with germ cell components, primary debulking surgery is crucial for prognosis. |
| Databáze: | OpenAIRE |
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