Synthesis, Properties, and Biological Activities of 2-Methyl- and 2-Styrylquinoline-4-Carboxylic Acids

Autor:	S. V. Ukhov, A. G. Goldshtein, R. R. Makhmudov, V. V. Novikova, A N Dubrovin, A. I. Mikhalev, T. F. Odegova
Rok vydání:	2015
Předmět:	Pharmacology Antifungal medicine.drug_class Chemistry Drug Discovery Pharmacology toxicology medicine Organic chemistry Antimicrobial Anti-inflammatory Biological Testing Catalysis
Zdroj:	Pharmaceutical Chemistry Journal. 49:309-312
ISSN:	1573-9031 0091-150X
DOI:	10.1007/s11094-015-1275-z
Popis:	Reaction of 2-methylquinoline-4-carboxylic acids with aromatic aldehydes in the presence of catalyst was performed to synthesize previously unknown 2-styrylquinoline-4-carboxylic acids. The structures of these compounds were verified using spectroscopic methods. Biological testing on animals showed that some of the resulting compounds had anti-inflammatory, analgesic, antimicrobial, and antifungal activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3ef1fb6f397b769a6ef02fb40b483545 https://doi.org/10.1007/s11094-015-1275-z Zobrazit plný text záznamu Plný text ve formátu PDF