| Popis: |
CI 1.049-1.132; p 0.001) for the exudates with the tumor. No difference was identified in location, multiplicity, intestinal metaplasia, growth pattern, and the infection of helicobater pylori between case and control groups. Dysplastic foci or carcinoma in hyperplastic polyps showed the loss of p16 expression (p 0.01) and the high expression of Ki-67 (p 0.02). However, the cyclin D1 and p53 expression did not show significant difference. Conclusions: Endoscopic removal about larger than 10mm sized hyperplastic polyp should be considered due to possibility of combined dysplasia or carcinoma. Loss of p16 with high Ki-67 expression can be used as markers of dysplasia associated with hyperplastic polyp. |
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