Comparison of Effectiveness of Nasal Continuous Positive Airway Pressure and Nasal Intermittent Positive Pressure Ventilation for the Initial Treatment of Preterm Respiratory Distress Syndrome: A Prospective Pilot Study

Autor:	Se Ra Min, Hyeon Soo Lee
Rok vydání:	2014
Předmět:	Respiratory distress business.industry medicine.medical_treatment Cardiorespiratory fitness General Medicine Intermittent positive pressure ventilation Anesthesia Breathing medicine Intubation Initial treatment Continuous positive airway pressure Respiratory system business
Zdroj:	Neonatal Medicine. 21:158
ISSN:	2287-9803 2287-9412
DOI:	10.5385/nm.2014.21.3.158
Popis:	Purpose: To compare respiratory and clinical outcomes between the currently used strategy of Intubation, Surfactant, Extubation (InSurE) and nasal continuous positive airway pressure (NCPAP) and the alternative strategy of InSurE and nasal intermittent positive pressure ventilation (NIPPV) for the initial treatment of respiratory distress syndrome (RDS) in preterm newborns ≤32 weeks. Methods: Twenty-six comparable preterm infants with RDS were included in the study; 13 were randomized to NCPAP and 13 to NIPPV. In both groups, the InSurE procedure consisted of intubation, surfactant instillation and 2 h positive pressure ventilation followed by extubation, after which spontaneously breathing newborns were placed on NCPAP or NIPPV. Results: There were no differences in demographic characteristics or cardiorespiratory status among preterm infants enrolled in the study. The reinutation rate was lower among the infants treated with NIPPV than among those on NCPAP (8% vs. 46%, P
Databáze:	OpenAIRE
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