Thermal stability of new biologic active copper(II) complexes with 5,6-dimethylbenzimidazole
| Autor: | Maria Nicoleta Grecu, Madalina Constand, Ioana Dorina Vlaicu, Mariana Carmen Chifiriuc, Rodica Olar, Dana Marinescu, Veronica Lazar, Mihaela Badea |
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| Rok vydání: | 2013 |
| Předmět: |
Denticity
Thermal decomposition Inorganic chemistry chemistry.chemical_element Condensed Matter Physics Copper Square pyramidal molecular geometry law.invention Dimethylbenzimidazole chemistry.chemical_compound chemistry law Polymer chemistry Molecule Thermal stability Physical and Theoretical Chemistry Electron paramagnetic resonance |
| Zdroj: | Journal of Thermal Analysis and Calorimetry. 113:1369-1377 |
| ISSN: | 1572-8943 1388-6150 |
| Popis: | Three new coordinative compounds that contain mixed ligands (5,6-dimethylbenzimidazole and acrylato anion) were synthesized and characterized. The features of complexes have been assigned from microanalytical, IR, UV–Vis and EPR spectra as well as thermal analysis. IR data are in accordance with unidentate nature of 5,6-dimethylbenzimidazole while the acrilato ion acts as uni- or bidentate ligand. The electronic spectra display the characteristic pattern of square pyramidal or octahedral stereochemistry, which were confirmed by the EPR spectra. Antibacterial and antifungal activities of the complexes have been determined in vitro, against various Gram-negative and Gram-positive bacteria and fungi. The tested complexes exhibited different spectra of antimicrobial activity and inhibited the microbial ability to colonize the inert surfaces, acting as potential anti-adherence and biofilm-controlling agents. Thermal decomposition evidenced several well-defined steps as dehydration (complex 2), 5,6-dimethylbenzimidazole molecule release (all complexes) and the acrylate decomposition in carbonate (complex 3). The final residue is in all cases copper (II) oxide. |
| Databáze: | OpenAIRE |
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