DOSE ESCALATION AND THE SAFETY OF CELECOXIB, IBUPROFEN, AND NAPROXEN: ANALYSIS OF THE PRECISION TRIAL

Autor: Mingyuan Shao, A M Lincoff, Kathy Wolski, Grant W. Reed, Mouin Abdallah, Neville Yeomans, Peter Libby, Thomas F. Luscher, Steven E. Nissen, Lisa Wisniewski, Elaine Husni, David Y. Graham, Jeffrey Borer, Venuy Menon, Daniel H. Solomon
Rok vydání: 2018
Předmět:
Zdroj: Journal of the American College of Cardiology. 71:A85
ISSN: 0735-1097
Popis: The PRECISION trial demonstrated the non-inferiority of celecoxib to ibuprofen or naproxen for cardiovascular (CV) safety in patients with arthritis. A comparison of the overall safety of each agent stratified by drug dose has yet to be reported. Patients were randomized to lower-dose celecoxib 100
Databáze: OpenAIRE