A phase 1/2 dose-escalation and expansion study of a conditionally active anti-AXL humanized monoclonal antibody (BA3011) in patients with advanced solid tumors

Autor: Eileen M. O'Reilly, Gerhard Frey, Jordi Rodon Ahnert, Matthew H. Taylor, Jingsong Zhang, Howard A. Burris, William J. Boyle, Michael Melnick, Wei Chen, Cathy Chang, Jay M. Short, Leslie L. Sharp, Yong Ben, Robert C. Doebele
Rok vydání: 2018
Předmět:
Zdroj: Journal of Clinical Oncology. 36:TPS12126-TPS12126
ISSN: 1527-7755
0732-183X
DOI: 10.1200/jco.2018.36.15_suppl.tps12126
Popis: TPS12126Background: The AXL receptor tyrosine kinase is often highly expressed in certain cancers. AXL appears to sustain resistance to anticancer therapies including chemotherapy, targeted therapy...
Databáze: OpenAIRE