Reaction of VX and GD with gaseous ozone †

Autor:	Barry R. Williams, George W. Wagner, John R. Stuff, William R. Creasy, Vikki D. Henderson, Mark D. Brickhouse, Joseph W. Hovanec, Philip W. Bartram, Theresa R. Connell, Kevin M. Morrissey
Rok vydání:	2000
Předmět:	chemistry.chemical_compound Ozone Pinacolyl Methylphosphonofluoridate chemistry Tertiary amine Inorganic chemistry medicine chemistry.chemical_element Medicinal chemistry Nitrogen Gaseous ozone Nerve agent medicine.drug
Zdroj:	Journal of the Chemical Society, Perkin Transactions 2. :1267-1272
ISSN:	1364-5471 1470-1820
Popis:	Attempts at decontaminating nerve agents VX {O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothioate} and GD (pinacolyl methylphosphonofluoridate) with gaseous ozone are described. VX reacts like a tertiary amine with oxidation occurring at carbons adjacent to the nitrogen. In this manner a variety of novel VX derivatives still possessing intact P–S bonds are generated, and as such, must be considered to retain formidable toxicity. The major product is O-ethyl S-[2-(isopropylamino)ethyl] methylphosphonothioate. No reaction of GD with ozone occurs under the conditions employed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3e79d2351de13241963e6775ef67fe6c https://doi.org/10.1039/a908187i Zobrazit plný text záznamu