A New Efficient Route to 2-Alkylsemicarbazides
Autor: | Anastasia A. Fesenko, Alexander S. Kuvakin, Ludmila A. Trafimova, Anatoly Shutalev, Maxim O. Zimin |
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Rok vydání: | 2019 |
Předmět: | |
Zdroj: | The 23rd International Electronic Conference on Synthetic Organic Chemistry. |
DOI: | 10.3390/ecsoc-23-06501 |
Popis: | Synthesis of hardly available 2-alkylsemicarbazides and their hydrochlorides from semicarbazide hydrochloride has been developed. This general and efficient protocol is based on preparation of acetone semicarbazone, its N2-alkylation in the presence of sodium hydride, and hydrolysis under mild conditions. |
Databáze: | OpenAIRE |
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