A New Efficient Route to 2-Alkylsemicarbazides

Autor: Anastasia A. Fesenko, Alexander S. Kuvakin, Ludmila A. Trafimova, Anatoly Shutalev, Maxim O. Zimin
Rok vydání: 2019
Předmět:
Zdroj: The 23rd International Electronic Conference on Synthetic Organic Chemistry.
DOI: 10.3390/ecsoc-23-06501
Popis: Synthesis of hardly available 2-alkylsemicarbazides and their hydrochlorides from semicarbazide hydrochloride has been developed. This general and efficient protocol is based on preparation of acetone semicarbazone, its N2-alkylation in the presence of sodium hydride, and hydrolysis under mild conditions.
Databáze: OpenAIRE