Obsessive-Compulsive Disorder in Adults with High-Functioning Autism Spectrum Disorder: What Does Self-Report with the OCI-R Tell Us?
Autor: | Nicola Gillan, C. Ellie Wilson, Declan G. Murphy, Ailsa Russell, Karen Glaser, David Mataix-Cols, Eileen Daly, Dene Robertson, Clodagh M. Murphy, Quinton Deeley, James Findon, Debbie Spain, Michael C. Craig, Maria Andreina Mendez, Patrick Johnston, Christine Ecker, Francesca Happé, Tim Cadman |
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Rok vydání: | 2015 |
Předmět: |
medicine.medical_specialty
genetic structures Receiver operating characteristic analysis General Neuroscience Adult population medicine.disease behavioral disciplines and activities humanities High-functioning autism Obsessive compulsive Autism spectrum disorder mental disorders medicine Autism Spectrum disorder Neurology (clinical) Psychology Psychiatry Self report Genetics (clinical) Clinical psychology |
Zdroj: | Autism Research. 8:477-485 |
ISSN: | 1939-3792 |
DOI: | 10.1002/aur.1461 |
Popis: | Little is known about the symptom profile of obsessive-compulsive disorder (OCD) in individuals who have autism spectrum disorders (ASD). It is also unknown whether self-report questionnaires are useful in measuring OCD in ASD. We sought to describe the symptom profiles of adults with ASD, OCD, and ASD + OCD using the Obsessive Compulsive Inventory-Revised (OCI-R), and to assess the utility of the OCI-R as a screening measure in a high-functioning adult ASD sample. Individuals with ASD (n = 171), OCD (n = 108), ASD + OCD (n = 54) and control participants (n = 92) completed the OCI-R. Individuals with ASD + OCD reported significantly higher levels of obsessive-compulsive symptoms than those with ASD alone. OCD symptoms were not significantly correlated with core ASD repetitive behaviors as measured on the ADI-R or ADOS-G. The OCI-R showed good psychometric properties and corresponded well with clinician diagnosis of OCD. Receiver operating characteristic analysis suggested cut-offs for OCI-R Total and Checking scores that discriminated well between ASD + versus –OCD, and fairly well between ASD-alone and OCD-alone. OCD manifests separately from ASD and is characterized by a different profile of repetitive thoughts and behaviors. The OCI-R appears to be useful as a screening tool in the ASD adult population. Autism Res 2015, 8: 477–485. © 2015 International Society for Autism Research, Wiley Periodicals, Inc. |
Databáze: | OpenAIRE |
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