Chimerism in scleroderma

Autor: Franklin Mullinax
Rok vydání: 1998
Předmět:
Zdroj: The Lancet. 351:1886
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(05)78834-6
Popis: 1presents evidence from PCR experiments that some women with scleroderma who have given birth to sons have male cells in their peripheral blood. Possibly these invaders cause scleroderma, and getting rid of them would cure patients with scleroderma. 2 Their hypothesis that autoimmune diseases are characterised by, indeed caused by, cell lines acquired during pregnancy—either mother-to-child or child-to-mother—is not original. Nor is the finding of male-cell determinants in the peripheral blood of patients with scleroderma by PCR. We have presented the hypothesis and PCR findings.
Databáze: OpenAIRE