| Autor: |
Ignác Capek |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Global Drugs and Therapeutics. :1-4 |
| DOI: |
10.31487/j.gdt.2020.01.02 |
| Popis: |
Need for materials with high biocompatible properties have led to the development of prodrug-decorated nanoparticles. The structure of present nanostructures consists of the hydrophobic core and hydrophilic shell. The shell acts as an external envelop which enhances the colloidal stability of dispersion which protects the prodrug of the nanoparticles from photo- and thermal-initiated degradation. The composite nanoparticles coated by organic shells with functional groups were considered to govern the covalent immobilization of therapeutics/biomolecules. The nanoparticles with unique physiochemical properties may be useful as biosensors in living whole cells. The enhanced cellular drug delivery to cancer cell lines via nanoconjugates revealed that smart nanoparticles are an effective tool for transporting and delivering drugs. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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