THE MAIN ASPECTS OF INVASIVE DISEASES TREATMENT AND PREVENTION IN TEENAGERS

Autor: M. A. Ezhned, I. M. Sakhatska, L. V. Kostyshyn, M. R. Matushchak, N. V. Mykhailiuk, O. I. Zakharchuk, V. I. Fediuk, O. M. Horoshko
Rok vydání: 2020
Předmět:
Zdroj: Clinical & experimental pathology. 19
ISSN: 1727-4338
DOI: 10.24061/1727-4338.xix.3.73.2020.10
Popis: In Ukraine, about 100,000 cases of geohelminthiasis are registered annually, 80%of which are children under 17 years of age. Symptoms of helminthiasis are mild orcompletely absent, but harmful to the body, however, infection of the child's body isespecially dangerous.Objective - to conduct a marketing study of drugs, used for treatment, and identify themain problems of this pathology prevention.Material and methods. A marketing research and analysis of the trade names’ market,analysis of 52 medical records of inpatients and outpatients (children aged 12 to 17years) for worm infestations and medical records of medical institutions in Chernivtsihave been carried out.Results. At the first stage of the research, a statistical study of invasive diseases state wasconducted and the main risk factors for infection were identified. We studied the rangeof antiparasitic drugs available on the domestic pharmaceutical market. Albendazole ismost often used as an active anthelmintic agent, 75% of which are domestic and 25% ofimported production. Preparations with the active substance pyrantel pamoate accountfor 42.8% of domestic production, all others are imported. According to the results of theprocessed medical records of patients several of the most common treatment regimens,which include anthelmintic therapy, the use of enterosorbents and the appointment ofa 5-day course prescription of H1-histamine receptor blockers were chosen. Havinganalyzed the average cost of the day treatment of nematode infestations, we came to theconclusion that the most available complex of group II drugs, the main antihelmintic drugis Zentel.One of the measures to prevent helminthiasis is the use of phytopreparations anddietary supplements based on medicinal plant materials, which, unlike chemicals, arecharacterized by milder properties and less toxicity, the ability not only to affect thepathogen directly, but also to restore the functional state of the organs and systemsaffected by worm infestation.Conclusions. From the offered schemes of pharmacotherapy the most accessible is theuse of a complex which structure includes Сarbowhite, Rolinoz, Zentel. It is promising tostudy the use of phytomedicines both during medical therapy and for prevention.
Databáze: OpenAIRE