Preparation of 5-(1-Aminocyclohexyl)-2(1H)-Pyridinones Via the Ritter Reaction

Autor:	Richard C. Effland, Fink David M
Rok vydání:	1994
Předmět:	Chemistry Yield (chemistry) Organic Chemistry Organic chemistry Reactivity (chemistry) Ritter reaction
Zdroj:	Synthetic Communications. 24:2793-2796
ISSN:	1532-2432 0039-7911
DOI:	10.1080/00397919408010597
Popis:	A series of 5-(1-aminocyclohexyl)-2(1H)-pyridinones was prepared in 16-32% yield. The key step is a Ritter reaction of the analogous alcohols. The results reported demonstrate the difference in reactivity between the closely related 2-alkoxy-pyridines and 2 (1H)-pyridinones.
Databáze:	OpenAIRE
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