ChemInform Abstract: Novel Synthesis of Fused Indoles and 2-Substituted Indoles by the Palladium-Catalyzed Cyclization of N-Cycloalkenyl-o-haloanilines
Autor: | Hiromichi Yamashita, Takeshi Watanabe, Shigeru Arai, Atsushi Nishida, Jun Maruyama |
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Rok vydání: | 2009 |
Předmět: | |
Zdroj: | ChemInform. 40 |
ISSN: | 1522-2667 0931-7597 |
Popis: | A new palladium-catalyzed cyclization of N-alkenyl-o-haloanilines with selective isomerization of a double bond followed by formal 5-endo-trig cyclization was developed. A variety of fused and 2-substituted indoles were synthesized from enaminoesters prepared by condensation of β-ketoesters and o-iodoaniline. |
Databáze: | OpenAIRE |
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