Behavioral mutants of Drosophila melanogaster. IV. Analysis of developmentally temperature-sensitive mutations affecting flight

Autor: Thomas A. Grigliatti, Theodore Homyk
Rok vydání: 1983
Předmět:
Zdroj: Developmental Genetics. 4:77-97
ISSN: 1520-6408
0192-253X
DOI: 10.1002/dvg.1020040204
Popis: Mutations in 13 genes with temperature-sensitive (ts), flightless phenotypes have been examined. All hop and fly well when raised at the permissive temperature, but fly poorly, or not at all, when raised at the restrictive temperature. The mutations were divided into three groups on the basis of their temperature-sensitive periods (TSPs) for flightlessness. The TSPs for mutations at five loci, fli-C1, D1, E1, I1, and shak A1, in the first group are confined to 24 to 48 hr interval during early pupal development. Mutations in the second group, including eag101, fli B1, and futs1 have continuous TSPs 3 to 4 days in length, extending from late larval through the early pupal stages. The flight TSPs for mutations in the third class, including fli J1, fli K2, flrd H3, and flrd N1, are almost continuous, and span most of the larval and pupal periods. Many of the mutations have pleiotropic phenotypes, including semilethality and lethality, and wing posture and cuticle abnormalities, with discernible TSPs. One of the more intriguing pleiotropic phenotypes is the ts optomotor response exhibited by fli J2, the TSP for which extends from late larval through late pupal stages.
Databáze: OpenAIRE
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