Changes in myocardial β-adrenergic receptors during acute rejection of heterotopically transplanted rat hearts
| Autor: | Mikio Ohmi, Sadayuki Murata, Iguchi A, Hitoshi Yokoyama, Hitoshi Mohri, Takahiko Nakame, Koichi Tabayashi |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Graft rejection Adrenergic receptor business.industry Histology Contractility Transplantation surgical procedures operative Endocrinology Cell surface receptor Internal medicine Lewis rats Medicine Surgery Cardiology and Cardiovascular Medicine business Receptor |
| Zdroj: | The Journal of Thoracic and Cardiovascular Surgery. 104:1567-1571 |
| ISSN: | 0022-5223 |
| DOI: | 10.1016/s0022-5223(19)33885-1 |
| Popis: | To evaluate changes of the myocardial β-adrenergic receptors in acute cardiac graft rejection, the density and binding affinity value of the myocardial β-adrenergic receptors in heterotopically transplanted rat isografts and allografts were analyzed. Hearts from Fisher rat donors were transplanted either to the Fisher rats (isografts) or to Lewis rats (allografts). Histologic examination of the allografts showed mild to moderate rejection on the seventh and fourteenth days and showed severe rejection on the twenty-first day after transplantation. The density values in the allografts and isografts similarly increased significantly (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|