ChemInform Abstract: Three-Component Diastereoselective Cascade Synthesis of Thiohydantoins

Autor:	Ramon Rios, Victor Ceban, Marta Meazza, Mark E. Light, Kane Hands
Rok vydání:	2014
Předmět:	Organic base Cascade reaction Cascade Component (thermodynamics) Chemistry General Medicine Combinatorial chemistry
Zdroj:	ChemInform. 45
ISSN:	0931-7597
Popis:	A new three-component cascade reaction for the synthesis of thiohydantoins is reported. The reaction between ?-amino esters, nitrostyrenes, and aromatic isothiocyanates is efficiently promoted by organic bases to afford highly substituted thiohydantoins in moderate to good yields and diastereoselectivities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3d87aa859417e531e1e18c08f5c4b46c https://doi.org/10.1002/chin.201417134 Zobrazit plný text záznamu Plný text