Synthesis and antitumor activity of 3-[(methyl)bis(5-trialkylsilyl-furan-2-yl)silyl]propylamines
Autor: | V. Romanov, J. Spura, Juris Popelis, I. Shestakova, L. Ignatovich, Ilona Domracheva |
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Rok vydání: | 2012 |
Předmět: | |
Zdroj: | Chemistry of Heterocyclic Compounds. 47:1502-1508 |
ISSN: | 1573-8353 0009-3122 |
Popis: | Novel 3-[(methyl)bis(5-trialkylsilylfuran-2-yl)silyl]propylamines have been synthesized by a hydrosilylation reaction of aliphatic and heterocyclic N-allylamines in the presence of the Speier's catalyst. The effects of the structure of the amine and the alkyl substituent at the silicon atom on the cytotoxicity of the compounds have been studied. |
Databáze: | OpenAIRE |
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