Synthesis and antitumor activity of 3-[(methyl)bis(5-trialkylsilyl-furan-2-yl)silyl]propylamines

Autor: V. Romanov, J. Spura, Juris Popelis, I. Shestakova, L. Ignatovich, Ilona Domracheva
Rok vydání: 2012
Předmět:
Zdroj: Chemistry of Heterocyclic Compounds. 47:1502-1508
ISSN: 1573-8353
0009-3122
Popis: Novel 3-[(methyl)bis(5-trialkylsilylfuran-2-yl)silyl]propylamines have been synthesized by a hydrosilylation reaction of aliphatic and heterocyclic N-allylamines in the presence of the Speier's catalyst. The effects of the structure of the amine and the alkyl substituent at the silicon atom on the cytotoxicity of the compounds have been studied.
Databáze: OpenAIRE