Antidepressant Reformulations: Who Uses Them, And What Are The Benefits?

Autor: Domino, M. E., Busch, A. B., Normand, S.-L. T., Huskamp, H. A.
Jazyk: angličtina
Rok vydání: 2009
DOI: 10.17615/zbfm-w788
Popis: The Hatch-Waxman Act provides pharmaceutical manufacturers an incentive to introduce reformulations of existing products about to lose patent protection in order to extend marketing exclusivity and maintain high prices. Antidepressant reformulations are particularly common. To determine whether antidepressant reformulation use confers benefits, we examine who uses reformulations, and compare medication continuation and the likelihood of receiving guideline-consistent pharmacotherapy duration among reformulation and original formulation users. We find some evidence of benefit for subgroups of antidepressant users, although benefits vary across reformulations.
Databáze: OpenAIRE