Autor: | V. V. Abramov, Vladimir A. Kozlov, E. V. Markova, E. V. Yakushenko, A. F. Poveshchenko, Korotkova Na |
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Rok vydání: | 2002 |
Předmět: |
Messenger RNA
medicine.medical_specialty Central nervous system Interleukin General Medicine Biology General Biochemistry Genetics and Molecular Biology Erythropoietin receptor Endocrinology Immune system medicine.anatomical_structure Internal medicine Interleukin-21 receptor medicine Receptor SOCS2 |
Zdroj: | Bulletin of Experimental Biology and Medicine. 133:65-67 |
ISSN: | 0007-4888 |
DOI: | 10.1023/a:1015112729103 |
Popis: | Interleukin-1beta mRNA, interleukin-1beta receptor mRNA, and erythropoietin receptor mRNA are expressed in the brain of (CBA×C57Bl)F1 mice. Immunization with sheep erythrocytes stimulated the expression of these cytokines in the cerebral hemispheres. Injection of recombinant erythropoietin reduced expression of interleukin-1beta, interleukin-1beta receptor, and erythropoietin receptor genes in the brain of experimental animals and considerably increased their motor activity in the open field test. |
Databáze: | OpenAIRE |
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