Analysis of the Diversity of Methicillin Resistant Staphylococcus aureus (MRSA) Strains Isolated from Diarrhea Patients in Busan Area
| Autor: | Jae-Hun Bin, Yon-Koung Park, Ho-Kuk Park, Joung-A Kim, Seong-Hwa Choi, Nam-Ho Kim, Young-Suk Lee, Eun-Hee Park |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
medicine.drug_class
SCCmec Antibiotics Enterotoxin biochemical phenomena metabolism and nutrition Biology bacterial infections and mycoses medicine.disease_cause Methicillin-resistant Staphylococcus aureus Microbiology Restriction fragment Diarrhea medicine Pulsed-field gel electrophoresis biology.protein Vancomycin medicine.symptom medicine.drug |
| Zdroj: | Journal of Life Science. 18:1083-1089 |
| ISSN: | 1225-9918 |
| DOI: | 10.5352/jls.2008.18.8.1083 |
| Popis: | We investigated the molecular epidemiological characteristic of methicillin resistant Staphylococcus aureus (MRSA) strains isolated from stool samples in Busan from 2004 to 2006. Among 142 isolates of S. aureus, 49 isolates (34.5%) were confirmed as MRSA. With the antimicrobial susceptibility tests, 37 isolates (75.5%) showed multiple resistance to more than 10 antibiotics, but all isolates were sensitive to vancomycin. All of MRSA had enterotoxin A in 30.6%, B 4.1%, C 8.3%, D, C/G, A 2.0% and None 51%. PFGE of SmaI-digested chromosomal DNA was performed on 49 sporadic MRSA isolates. Restriction fragment patterns consisted of 8 to 14 fragments ranged in size from 48.5 to 630.5 kbp. We could divided the isolates into 7 groups () by analyzing PFGE patterns. Group I subdivided as 2 subgroups and 17 (34.7%) strains belong to the group I. Dendrogram of PFGE patterns showed that MRSA strains in Busan were heterogeneous but we could find out minor homogeneity in hospital. |
| Databáze: | OpenAIRE |
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