First molecular characterization and phylogenetic analysis of the VP2 gene of feline panleukopenia virus in Bangladesh

Autor: Q M Monzur Kader Chowdhury, M. M. Hossain, Shahrul Alam, Masudur Rahman, Mahfujur Rahman, Rafiqul Islam, Mahmudul Hasan, Shahidur Rahman Chowdhury, Bashir Uddin
Rok vydání: 2021
Předmět:
Zdroj: Archives of Virology. 166:2273-2278
ISSN: 1432-8798
0304-8608
DOI: 10.1007/s00705-021-05113-y
Popis: Feline panleukopenia virus (FPV) is a highly contagious infectious pathogen of cats globally. However, there is no information on the molecular identification and characterization of FPV in Bangladesh. Here, 8.16% (8/98) and 18.37% (18/98) of diarrheic cats tested positive for FPV by an immunochromatography (IC) test and PCR, respectively. The IC test showed 44.44% sensitivity and 100% specificity in comparison with PCR. Our newly sequenced Bangladeshi FPV strain (MN826076) showed the highest (99.71%) sequence identity to strains from the United Arab Emirates (UAE). Strain MN826076 contained two characteristic amino acid variations in VP2 identifying it as an FPV strain: valine at position 103 and aspartic acid at position 323. Phylogenetically, the VP2 of strain MN826076 was found to be closely related to 19 FPV strains, sharing the same clade.
Databáze: OpenAIRE
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