WITHDRAWN: Dexamethasone effect on postoperative pain of thyroid surgery: A meta-analysis of randomized controlled trials

Autor:	Chuan Shi, Buhuai Dong, Tao Xu, Liangku Huang, Xucai Wu, Hui Yang
Rok vydání:	2020
Předmět:	medicine.medical_specialty Nausea business.industry Thyroid Perioperative Cochrane Library Placebo Surgery law.invention medicine.anatomical_structure Otorhinolaryngology Randomized controlled trial law Vomiting medicine medicine.symptom business Dexamethasone medicine.drug
Zdroj:	American Journal of Otolaryngology. :102669
ISSN:	0196-0709
DOI:	10.1016/j.amjoto.2020.102669
Popis:	Introduction The effect of dexamethasone on postoperative pain after thyroid surgery remains controversial. We conduct a systematic review and meta-analysis to explore the influence of dexamethasone versus placebo on postoperative pain after thyroid surgery. Methods We search PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases through May 2020 for randomized controlled trials (RCTs) assessing the effect of dexamethasone versus placebo on postoperative pain after thyroid surgery. This meta-analysis is performed using the random-effect model. Results Eight RCTs involving 734 patients are included in the meta-analysis. Overall, compared with control group for thyroid surgery, dexamethasone shows significantly reduced pain scores (SMD = -0.82; 95% CI = -1.08 to −0.56; P Conclusions Perioperative dexamethasone is effective to reduce the pain, nausea and vomiting after thyroid surgery.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3d3ed8fcbdda3907be2b9dabee1197a2 https://doi.org/10.1016/j.amjoto.2020.102669 Zobrazit plný text záznamu Full Text from ScienceDirect