Mirror aneurysms: a reflection on natural history
| Autor: | Irene Meissner, James Torner, John Huston, Michele L. Rajput, David O. Wiebers, Lyell K. Jones, Robert D. Brown |
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| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
Subarachnoid hemorrhage medicine.diagnostic_test business.industry General Medicine medicine.disease Surgery Natural history Aneurysm cardiovascular system Medicine cardiovascular diseases Radiology Family history business Prospective cohort study Chi-squared distribution Cerebral angiography Cause of death |
| Zdroj: | Journal of Neurosurgery. 116:1238-1241 |
| ISSN: | 1933-0693 0022-3085 |
| DOI: | 10.3171/2012.1.jns11779 |
| Popis: | Object Investigators conducting the International Study of Unruptured Intracranial Aneurysms, sponsored by the National Institutes of Health, sought to evaluate predictors of future hemorrhage in patients who had unruptured mirror aneurysms. These paired aneurysms in bilateral arterial positions mirror each other; their natural history is unknown. Methods Centers in the US, Canada, and Europe enrolled patients for prospective assessment of unruptured intracranial aneurysms. Central radiological review confirmed the presence or absence of mirror aneurysms in patients without a history of prior subarachnoid hemorrhage (SAH) (Group 1). Outcome at 1 and 5 years and aneurysm characteristics are compared. Results Of 3120 patients with aneurysms treated in 61 centers, 376 (12%) had mirror aneurysms, which are more common in women than men (82% [n = 308] vs 73% [n = 1992], respectively; p Compared with patients with nonmirror saccular aneurysms, a greater percentage of patients with mirror aneurysms had larger (>10 mm) aneurysms (mean maximum diameter 11.7 vs 10.4 mm, respectively; p Conclusions Overall, patients with mirror aneurysms were more likely to be women, to report a family history of aneurysmal SAH, and to have larger aneurysms. The presence of a mirror aneurysm was not an independent predictor of future SAHs. |
| Databáze: | OpenAIRE |
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