Regulation of Ovarian Inhibin and Activin Gene Expression by Gonadotropins
| Autor: | Ok-Kyong Park, Robin E. Dodson, Joanna C. Dykema, Kelly E. Mayo, Lin Pei |
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| Rok vydání: | 1992 |
| Předmět: |
endocrine system
medicine.medical_specialty endocrine system diseases Granulosa cell luteinizing hormone/choriogonadotropin receptor Biology Follicular fluid female genital diseases and pregnancy complications Paracrine signalling Follicle-stimulating hormone Endocrinology Internal medicine Follicular phase medicine Luteinizing hormone hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | Follicle Stimulating Hormone ISBN: 9781468471052 |
| DOI: | 10.1007/978-1-4684-7103-8_13 |
| Popis: | Follicle stimulating hormone (FSH) plays a critical role in regulating ovarian function and is a key hormone in initiating follicular recruitment and promoting follicular maturation (1). Additionally, it influences differentiation by modulating steroidogenesis, inducing luteinizing hormone receptors and regulating the synthesis of ovarian hormones, such as inhibin and activin. Inhibin is an important regulator of FSH synthesis and secretion in rats (2), while activin appears to be a paracrine regulator of ovarian function (3, 4) that may also be involved in FSH regulation (5, 6). The study of how these two genes are regulated is important for understanding aspects of the reproductive cycle. This report focuses on the regulation of inhibin and activin gene expression in rat granulosa cells (GC) by gonadotropins. |
| Databáze: | OpenAIRE |
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