Agatston calcium score, CHA2DS2-VASc and HAS-BLED in patients before atrial fibrillation ablation

Autor: L. Christiaens, E. Grobost-Dalbin, R. Garcia
Rok vydání: 2019
Předmět:
Zdroj: Archives of Cardiovascular Diseases Supplements. 11:e285
ISSN: 1878-6480
DOI: 10.1016/j.acvdsp.2019.01.007
Popis: Background Clinical scores of thrombo-embolism risk (CHA2DS2-VASc) and hemorrhagic risk (HAS-BLED) have been developed to characterize the patients with non-valvular atrial fibrillation. These scores have been defined in part with clinical risk factors of atherosclerosis. Before their ablation, a coronary computed tomography angiography enables to determine the Agatston calcium score (coronary artery calcium score) which is a atherosclerosis marker. Purpose In this study,we tried to find out a link between the Agatston calcium score and the CHA2DS2-VASc, as well as between the Agatston calcium score and the HAS-BLED. Methods In total, 344 atrial fibrillation subjects were included in our observational and retrospective study between January 1st, 2013 and January 1st, 2017, in the same institute. All of these patients had undergone a coronary computed tomography angiography. Results Three hundred and seventeen patients were included in this study: 233 men (73.5%) and 84 women (26.5%), with an average age of 60.4 years. Agatston calcium score was significantly higher in the subjects with CHA2DS2-VASc score ≥ 2 (P This link is also found between the Agatston calcium score and the HAS-BLED score ≥ 2 (P Conclusion This study shows a strong link between the atherosclerosis marker determined by CT (coronary artery calcium score), the thrombo-embolism risk score (CHA2DS2-VASc) and the hemorrhagic risk score (HAS-BLED) determined by clinical elements in patients with non-valvular atrial fibrillation.
Databáze: OpenAIRE