Deep Brain Stimulation
| Autor: | Darin D. Dougherty |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Movement disorders Deep brain stimulation Neurology business.industry medicine.medical_treatment medicine.disease 030227 psychiatry Clinical trial 03 medical and health sciences Psychiatry and Mental health 0302 clinical medicine Physical medicine and rehabilitation Deep brain stimulation electrode medicine medicine.symptom business Treatment-resistant depression 030217 neurology & neurosurgery Depression (differential diagnoses) Tractography |
| Zdroj: | Psychiatric Clinics of North America. 41:385-394 |
| ISSN: | 0193-953X |
| Popis: | Deep brain stimulation has been used for decades in neurology to treat movement disorders. More recent work has focused on developing applications for deep brain stimulation in psychiatric illness. Initial studies have demonstrated positive results for treatment-refractory obsessive-compulsive disorder. Initial open-label studies of deep brain stimulation at targets for treatment-resistant depression have been encouraging. However, the only 2 published controlled trials that were conducted for potential FDA approval for treatment-resistant depression were both negative. Future directions include potential use of alternate clinical trial designs, using tractography for more refined deep brain stimulation electrode targeting, and closed-loop deep brain stimulation approaches. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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