Microfluidic biochip and integrated diffractive optics for bacteria growth control and monitoring
| Autor: | M. Cynthia Goh, Vitali Borisenko |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Diffraction Materials science General Chemical Engineering 030106 microbiology Microfluidics General Engineering Nanotechnology Bacterial growth Signal Analytical Chemistry Trap (computing) 03 medical and health sciences 030104 developmental biology Exponential growth Monolayer bacteria Biochip |
| Zdroj: | Analytical Methods. 9:2392-2396 |
| ISSN: | 1759-9679 1759-9660 |
| DOI: | 10.1039/c6ay03311c |
| Popis: | We present a simple and inexpensive method for enabling bacterial cell capture in a 2D array of traps, such that their growth can be monitored under controlled dynamic environments through diffractive optics integrated into a microfluidic chip. As an example, we demonstrate the feasibility for E. coli capture and expansion within the monolayer trap; the resulting increase in the diffraction signal is consistent with the cells' exponential growth rate. |
| Databáze: | OpenAIRE |
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