Studies of insect peptides alloferon, Any -GS and their analogues. Synthesis and antiherpes activity
| Autor: | Anna Midak-Siewirska, Danuta Konopińska, Mariola Kuczer, Renata Zahorska, Mirosław Łuczak, Katarzyna Dziubasik |
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| Rok vydání: | 2010 |
| Předmět: |
Pharmacology
viruses Human herpes virus media_common.quotation_subject Organic Chemistry Bombesin General Medicine Insect Biology Biological effect Biochemistry Virology In vitro chemistry.chemical_compound chemistry Structural Biology Biological property Drug Discovery Vero cell Molecular Medicine Molecular Biology media_common |
| Zdroj: | Journal of Peptide Science. 16:186-189 |
| ISSN: | 1075-2617 |
| DOI: | 10.1002/psc.1219 |
| Popis: | The subject of these studies was synthesis and determination of biological properties of a series of insect peptides, such as alloferon, Any-GS and their analogues. The synthesis of 14 peptides was performed by the solid-phase method. Biological effect of these peptides was evaluated by the antiviral test against Human Herpes Virus type 1 (HHV-1) in vitro using a Vero cell line. It was found that the investigated peptides inhibit the replication of HHV-1 in Vero cells. |
| Databáze: | OpenAIRE |
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