CLINICAL AND PATHOLOGICAL SIGNIFICANCE OF ASYMPTOMATIC ATROPHIC THYROIDITIS

Autor: Marc Bonnyns, Paul Auguste Bastenie, M. Chailly, Pierre Neve, Luc Vanhaelst
Rok vydání: 1967
Předmět:
Zdroj: The Lancet. 289:915-919
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(67)91486-9
Popis: By the Boyden tanned-red-cell test, thyroglobulin antibodies (T.G.A.) have been detected in a large percentage of over 2000 patients admitted to hospital for various diseases. Post-mortem controls in nearly 250 cases with and without circulating T.G.A. have indicated a very high correspondence of these antibodies with the presence of a process of atrophic asymptomatic thyroiditis. This condition, which is to be distinguished from Hashimoto's thyroiditis, is prevalent in women and its incidence increases with age. Its development is associated with other autoimmune diseases, with diabetes, and with obesity. Although clinical signs of hypothyroidism are absent, biological signs are indicative of latent thyroid failure.
Databáze: OpenAIRE