Abnormal or absent β mRNA in β0 Ferrara and gene deletion in δβ thalassaemia
| Autor: | G Pizzarelli, Russo G, Francesco Ramirez, Paul A. Marks, Gino Schilirò, Salvatore Musumeci, Arthur Bank, Roberto Gambino, Benedetta Luppis, Joyce V. O'Donnell |
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| Rok vydání: | 1976 |
| Předmět: |
Genetics
congenital hereditary and neonatal diseases and abnormalities Messenger RNA Globin genes Multidisciplinary Thalassemia Gene deletion Biology medicine.disease Molecular biology chemistry.chemical_compound Nucleic acid thermodynamics chemistry hemic and lymphatic diseases medicine In patient Gene DNA |
| Zdroj: | Nature. 263:471-475 |
| ISSN: | 1476-4687 0028-0836 |
| DOI: | 10.1038/263471a0 |
| Popis: | In patients with betao thalassaemia from Ferrara, beta globin mRNA sequences are either absent or structurally abnormal while in betao thalassaemia in Catania, beta globin mRNA sequences are present. In deltabeta thalassaemia there is a deletion of beta-like globin genes, while in betao Catania DNA, no beta globin gene deletion is detectable. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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