| Autor: |
Marie-Pier Cloutier, Martin Leduc, Brigitte Grouix, Shaun D. Abbott, Mikaël Tremblay, Alexandre Laverdure, Kathy Hince, Boulos Zacharie, Lyne Gagnon, Lilianne Geerts, Jean-Simon Duceppe, François Sarra-Bournet, Liette Gervais, Pierre Laurin |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
QJM: An International Journal of Medicine. |
| ISSN: |
1460-2393 |
| Popis: |
PBI-4050 is a first-in-class orally active compound which displays antifibrotic activities in kidney, heart, liver, pancreas and lung models. PBI-4050 was found to be safe and well tolerated in healthy volunteers and in patients with CKD and Type 2 diabetes without any SAEs. Translation of pharmacological efficacy in humans … |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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