Synthesis of a 5-alkoxypyrido[3,4-d]pyrimidin-4(3H)-one derivative via directed ortho-metallation of a pyridine analogue

Autor:	Johnson Paul David, Allan Dishington, Jason Grant Kettle
Rok vydání:	2004
Předmět:	Organic Chemistry chemistry.chemical_element Biochemistry Combinatorial chemistry Catalysis chemistry.chemical_compound Carboxylation chemistry Drug Discovery Pyridine Organic chemistry Derivative (chemistry) Amination Palladium
Zdroj:	Tetrahedron Letters. 45:3733-3735
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2004.03.087
Popis:	The synthetic strategy towards a 5-alkoxypyrido[3,4-d]pyrimidin-4(3H)-one is described, utilizing palladium catalyzed amination of a bromopyridine, and subsequent directed ortho-metallation/carboxylation as the key steps.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3ceb8bd7f44b772a106fbc252b3a495c https://doi.org/10.1016/j.tetlet.2004.03.087 Zobrazit plný text záznamu Full Text from ScienceDirect