Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin

Autor:	I. V. Mil’to, Irina V. Saltykova, Alexandra G. Pershina, Sh. Yu. Khapchaev, S. S. Gutor, I. V. Petrova, N. S. Subbotina, E. E. Kremer, Ilya P. Kaminskii, S. V. Krivoshchekov, K. V. Khvorilova
Rok vydání:	2013
Předmět:	Programmed cell death Endosome Toxin medicine.drug_class Compartment (chemistry) Biology medicine.disease_cause Monoclonal antibody General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound Cytosol Ricin chemistry Biochemistry medicine Biophysics General Agricultural and Biological Sciences Intracellular General Environmental Science
Zdroj:	Moscow University Biological Sciences Bulletin. 68:174-177
ISSN:	1934-791X 0096-3925
Popis:	Data on volume of the intracellular compartment where the internalized toxin is located and toxin concentration in this compartment have been obtained. Suggestions have been made about a role of toxin molecule aggregates in the translocation of A-chain into cytosol, which leads to cell death.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3cc40267a8bf4c0090a6934aef0719a1 https://doi.org/10.3103/s0096392514010040 Zobrazit plný text záznamu Full text from SpringerLink