| Autor: |
A. Hamid Kazerouni, Runjan Chetty |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
Diagnostic Histopathology. 19:311-313 |
| ISSN: |
1756-2317 |
| DOI: |
10.1016/j.mpdhp.2013.06.012 |
| Popis: |
Solitary coin lesions in the lung invoke an expanding differential diagnosis and while pulmonary hamartoma and a neuroendocrine tumour are the commonest causes, there are other lesions that need to be considered. Alveolar adenoma and sclerosing pneumocytoma are two such lesions. This is a case of an alveolar adenoma in a 41-year-old asymptomatic female who was found to have a peripheral solitary lesion on routine chest X-ray. In view of suspicious cytology, she had a left lower lobectomy. The lesion was well-circumscribed and composed of multiple cystic structures of varying size. The cysts were lined by epithelial cells ranging from flat to cuboidal to hobnail, and conformed to type II pneumocytes. The stroma between the cysts contained bland spindle shaped cells and mixed inflammation, including several mast cells. Immunohistochemistry showed the cyst lining cells to be positive for epithelial markers and TTF-1. The stromal cells were negative for these stains. Alveolar adenoma is a rare benign cystic neoplasm of lung with a superficial resemblance to a lymphangioma and is thought to arise from type II pneumocytes. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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Full Text from ScienceDirect