Investigation of Genotoxicity of Gold Nanoparticles Prepared by the Electric Spark Dispersion Method

Autor:	Andrew Gapeyev, Dmitry Martemiyanov, S. P. Zhuravkov, Vladimir S. Plotnikov, Evgenii Plotnikov
Rok vydání:	2014
Předmět:	Materials science General Engineering Analytical chemistry Thermal desorption chemistry.chemical_element medicine.disease_cause Nitrogen Comet assay chemistry Transmission electron microscopy Colloidal gold medicine Electric spark Dispersion (chemistry) Genotoxicity Nuclear chemistry
Zdroj:	Advanced Materials Research. 1040:65-69
ISSN:	1662-8985
DOI:	10.4028/www.scientific.net/amr.1040.65
Popis:	The paper presents the results of investigations of genotoxicity and morphological characteristics of nanoscale gold particles prepared by the electric spark dispersion method in a water medium. To investigate the properties we used comet assay, transmission electron microscopy, thermal desorption of nitrogen (BET). It was revealed, gold particles did not cause DNA damage at low concentrations (0.01 - 0.1 mg/ml) and detectable level of genotoxicity of gold nanoparticles is observed at concentrations of 0.3 mg/ml and above.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3c9dd9d0c8ab12ab84951fb3f1de38f1 https://doi.org/10.4028/www.scientific.net/amr.1040.65 Zobrazit plný text záznamu