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Bioactivity guided separation of combined n-hexane and chloroform extracts of Oplismenus burmannii resulted in the isolation and characterization of five new glycoglycerolipids, (2S)-1,2,6’-tri- O -hexadecanoyl-3- O -β-D-galactopyranosyl glycerol (1a), (2S)-1,2,6’-tri- O -[(9Z,12Z)-octadeca-9,12- dienoyl]-3- O -β-D-galactopyranosyl glycerol (1b), (2S)-1,6’-di- O -[(9Z,12Z)-octadeca-9,12-dienoyl]-3- O -β-D-galactopyranosyl glycerol (2b), (2S)-1,6’-di- O -[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]-3- O -β-D-galactopyranosyl glycerol (2c), and (2S)-1,2-di- O -[(9Z,12Z)-octadeca-9,12-dienoyl]-3- O -(6- sulpho-α-D)-quinovopyranosyl glycerol (3b) along with five known glycoglycerolipids (1c, 2a, 3a, 3c and 4), a cerebroside (5), three monoacylglycerols (6a-c) and α-linoleic acid (7). The isolated compounds, 1-5 were in-vitro tested for their antihyperglycemic potential in terms of increase in 2-deoxyglucose uptake in L6-GLUT4 myc myotube cells. The results showed that compounds, 1-5 were showing 1.52 (P |
