Synthesis and Biological Evaluation of Novel 1, 3, 4-Thiadiazole Heterocyclic Derivatives as Novel Anti-Microbial Agents

Autor:	M. Hari Krishna, K. Murali, Thuraka Sekhar, P. Thriveni
Rok vydání:	2016
Předmět:	chemistry.chemical_compound chemistry Core component Anti-Microbial Agents Biology Pharmacophore Hydrazide Antimicrobial Heterocyclic derivatives Combinatorial chemistry Biomedical engineering Biological evaluation
Zdroj:	Asian Journal of Research in Chemistry. 9:107
ISSN:	0974-4150 0974-4169
Popis:	Heterocyclic compounds are commonly used Scaffolds on which pharmacophores are arranged to provide potent and selective drugs. This is especially true for five-membered ring heterocyclic compounds, which serve as the core components of many substances that possess a wide range of interesting biological activities. New series of 1, 3, 4-Thiadiazole derivatives were synthesized From Benzyl Isocynate and Acid hydrazide, by using P-TsCl in NMP, The Novel Derivatives have been screened for their antimicrobial activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3c5491130cb11652b987146984327894 https://doi.org/10.5958/0974-4150.2016.00019.5 Zobrazit plný text záznamu