Intermittent hypoxia enhances shear-mediated dilation of the internal carotid artery in young adults
| Autor: | Brady E. Hanson, Joshua M. Bock, Erika Iwamoto, Darren P. Casey |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Physiology business.industry Intermittent hypoxia 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Physiology (medical) Internal medicine medicine.artery cardiovascular system Cardiology Dilation (morphology) Medicine Young adult medicine.symptom Internal carotid artery business Hypercapnia 030217 neurology & neurosurgery |
| Zdroj: | Journal of Applied Physiology. 129:603-611 |
| ISSN: | 1522-1601 8750-7587 |
| DOI: | 10.1152/japplphysiol.00274.2020 |
| Popis: | We explored the effects of cyclic intermittent hypoxia (IH) on shear-mediated dilation of the internal carotid artery (ICA), a potential index of cerebral endothelial function, in young adults. Cyclic IH increased blood flow and shear rate in the ICA and, as a result, increased shear-mediated dilation of the ICA. These data suggest that cyclic IH could potentially be applied as a nonpharmacological therapy to optimize cerebral vascular health. |
| Databáze: | OpenAIRE |
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