Preemptive analgesia with controlled-release oxycodone is successful in prevention of post-inguinal herniorrhaphy pain

Autor: Gregory Fleishman, Juan Carlos Cozacov, Igor Dashkovsky, Semion Asaulenco
Rok vydání: 2004
Předmět:
Zdroj: Ambulatory Surgery. 11:11-13
ISSN: 0966-6532
DOI: 10.1016/j.ambsur.2004.04.001
Popis: In a double-blind randomized study, controlled-release (CR) oxycodone (OxyContin ®) administration was assessed against placebo to ascertain the extent of postinguinal herniorrhaphy pain control. Patients received a single dose of CR oxycodone (40 mg orally) or placebo 40 min before surgery. When post-surgical pain was first reported, a visual analogue scale (VAS) was used to assess pain score. Postoperative pain-free time, dolestin (opiod) and dipyrone (antipyretic) consumption were assessed 24 h after the surgery. Postoperative pain-free time in the CR oxycodone group (Group I) was 655±548 min versus 112±71.5 min in the placebo group (Group II) (P
Databáze: OpenAIRE