ELECTRON MICROSCOPIC STUDIES OF ANTERIOR PITUITARY GLANDS FROM LACTATING AND ESTROGEN-TREATED RATS1

Autor:	R. G. Christiansen, W. C. Hymer, W. H. McShan
Rok vydání:	1961
Předmět:	medicine.medical_specialty medicine.drug_class Endoplasmic reticulum Biology law.invention Endocrinology medicine.anatomical_structure Anterior pituitary Estrogen law Lactation Internal medicine medicine Electron microscope Electron microscopic Reticulum Acidophil cell
Zdroj:	Endocrinology. 69:81-90
ISSN:	1945-7170 0013-7227
Popis:	Anterior pituitary glands from mature virgin female, estrogen, treated, and lactating rats were studied with the electron microscope. It was found that the endoplasmic reticulum underwent extensive change during lactation. A similar situation was also found in the pituitaries of the estrogen treated animals. This well developed reticulum was localized mainly in the acidophils with 600 mμ granules, indicating these cells are probably responsible for the elaboration of lactogenic hormone. In addition to thin sections for electron microscopy, thick sections were taken for light microscopy. The pituitaries from the animals which were injected with estrogen were assayed for lactogenic hormone. On the basis of these results and those of others a scheme is presented for production and release of lactogenic hormone from certain of the acidophilic cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3c36f12806e09d05784eda29e900bb43 https://doi.org/10.1210/endo-69-1-81 Zobrazit plný text záznamu