| Autor: |
Laimer, Markus, Schütz-Fuhrmann, Ingrid, Melmer, Andreas, Engels, Heide-Rose, Holl, Reinhard W, Pfeifer, Martin, Hermann, Julia M, Götz, Gabriele, Stettler, Christoph, Mader, Julia K |
| Jazyk: |
angličtina |
| Předmět: |
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| Popis: |
BACKGROUND Traditionally, basal rate profiles in continuous subcutaneous insulin infusion therapy are individually adapted to cover expected insulin requirements. However, whether this approach is indeed superior to a more constant BR profile has not been assessed so far. This study analysed the associations between variability of BR profiles and acute and chronic complications in adult type 1 diabetes mellitus. MATERIALS AND METHODS BR profiles of 3118 female and 2427 male patients from the "Diabetes-Patienten-Verlaufsdokumentation" registry from Germany and Austria were analysed. Acute and chronic complications were recorded 6 months prior and after the most recently documented basal rate. The "variability index" was calculated as variation of basal rate intervals in percent and describes the excursions of the basal rate intervals from the median basal rate. RESULTS The variability Index correlated positively with severe hypoglycemia (r = .06; p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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