Lipoprotein lipids in chronic renal failure and haemodialysis
| Autor: | Lynn K. Abbott, R. B. Blacket, John B. Somer, John A. Charlesworth, Janet M. Aitken, Graham J. Macdonald |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
medicine.medical_specialty
Very low-density lipoprotein Triglyceride business.industry Cholesterol Arteriosclerosis Analgesic nephropathy medicine.disease chemistry.chemical_compound Endocrinology High-density lipoprotein chemistry Internal medicine Low-density lipoprotein medicine lipids (amino acids peptides and proteins) Cardiology and Cardiovascular Medicine business Lipoprotein |
| Zdroj: | Atherosclerosis. 34:353-364 |
| ISSN: | 0021-9150 |
| Popis: | Lipoprotein lipid analysis has been carried out in 39 women and 28 men with chronic renal failure on haemodialysis. The results have been analysed in relation to the etiology of the renal disease and compared with those obtained in age- and sex-matched controls and in triglyceride-matched controls. Serum cholesterol was normal or low in glomerulonephritis but was normal in analgesic nephropathy. Serum triglycerides and VLDL lipids were raised uniformly regardless of the etiology of the renal disease. LDL triglyceride and HDL triglyceride were also raised. LDL cholesterol and phospholipid were low in glomerulonephritis but were normal in analgesic nephropathy. HDL cholesterol was reduced in both male and female patients regardless of etiology, statistical significance was not reached for the women. The ratio of esterified to free cholesterol tended to be reduced in all the lipoproteins regardless of sex or etiology but the changes were not significant in all groups. Comparison of the lipid abnormalities with those found in other hyperlipidaemic states suggests that the lipid disorders found in chronic renal failure are probably insufficient to explain the rapid development of vascular disease which has been reported. |
| Databáze: | OpenAIRE |
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