A Convex Hull-Based New Metric for Quantification of Bladder Wall Irregularity in Pediatric Patients With Congenital Anomalies of the Kidney and Urinary Tract
| Autor: | Gerald Behr, Joseph N. Stember, Shumyle Alam, Jeffrey H. Newhouse |
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| Rok vydání: | 2017 |
| Předmět: |
Convex hull
medicine.medical_specialty Kidney 030219 obstetrics & reproductive medicine Radiological and Ultrasound Technology business.industry Urinary system Disease progression 030232 urology & nephrology Urology urologic and male genital diseases Confidence interval Surgery 03 medical and health sciences Normal renal function 0302 clinical medicine medicine.anatomical_structure Medicine Effective treatment Radiology Nuclear Medicine and imaging Metric (unit) business |
| Zdroj: | Journal of Ultrasound in Medicine. 36:2203-2208 |
| ISSN: | 0278-4297 |
| DOI: | 10.1002/jum.14270 |
| Popis: | Objectives Early identification and quantification of bladder damage in pediatric patients with congenital anomalies of the kidney and urinary tract (CAKUT) is crucial to guiding effective treatment and may affect the eventual clinical outcome, including progression of renal disease. We have developed a novel approach based on the convex hull to calculate bladder wall trabecularity in pediatric patients with CAKUT. The objective of this study was to test whether our approach can accurately predict bladder wall irregularity. Methods Twenty pediatric patients, half with renal compromise and CAKUT and half with normal renal function, were evaluated. We applied the convex hull approach to calculate T, a metric proposed to reflect the degree of trabeculation/bladder wall irregularity, in this set of patients. Results The average T value was roughly 3 times higher for diseased than healthy patients (0.14 [95% confidence interval, 0.10–0.17] versus 0.05 [95% confidence interval, 0.03–0.07] for normal bladders). This disparity was statistically significant (P |
| Databáze: | OpenAIRE |
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